Editorial: Advances in Pediatric Renal Transplantation
نویسندگان
چکیده
منابع مشابه
Advances in Pediatric Renal Transplantation
The science of kidney transplantation in children has advanced remarkably in the last 40 years [1, 2]. As kidney transplants in adult recipients were becoming more common with improving shortand long-term outcomes, results in children were lagging behind. This lag was attributed to multiple factors: greater surgical and technical problems in small children, different metabolism for needed drugs...
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Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease and is considered a common pathway leading to end-stage of renal failure. Renal fibrosis involves a complex interplay between intrinsic kidney cells, leukocytes, and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. Inhibition of TGF-β1 suppresses renal fibrosis i...
متن کاملPediatric renal transplantation--Indian experience.
OBJECTIVE To analyze our experience with renal transplantation in children with end-stage renal disease (ESRD) in India. DESIGN Retrospective study. METHODS Over the last 7.5 years, 27 renal transplants were performed on children below 12 years of age, 8 children were less than 6 years old, 19 were between 6 and 12 years of age. Sixteen children had underlying glomerular disease while eleve...
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TACROLIMUS has been shown to be a safe and effective immunosuppressive agent in adult renal transplantation with significant advantages, including the ability to taper corticosteroids in up to 65% of recipients. 1-4 The use of this agent in the pediatric population is less well described. We and others have previously reported that its use in pediatric patients is associated with excellent pati...
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A retrospective analysis was done on 47 pediatric renal transplants performed over last 16 years at Bangalore, Karnataka. The median age and weight of the recipients at transplantation were 120 months and 21 kg respectively; male to female ratio was 30 to 17. Twenty two children had underlying glomerular disease and 23 had tubulointerstitial disease. Preemptive transplantation was done in 33.3%...
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ژورنال
عنوان ژورنال: The Open Urology & Nephrology Journal
سال: 2014
ISSN: 1874-303X
DOI: 10.2174/1874303x01407010113